The Danish National Genome Center represents Denmark in the European 1+ Million Genomes (1+MG) Initiative, which originated in 2018. The aim of the initiative is to enable secure access to genome data across Europe. The vision is that genome data should be accessible across borders, but without data being sent out of the individual countries. Analysis must be carried out locally and results can subsequently be combined across different countries. The focus is on disease prevention, diagnostics, personalized medicine and research.
The Danish National Genome Center also participates in the Genomic Data Infrastructure Project (GDI) which is part of the implementation of the 1+MG initiative. The aim of the project is to build a secure and long-term federated data infrastructure, where metadata is exhibited on a common European platform and where data (in pseudonymized form) can only be accessed within the individual countries. Only the results of the analysis can be sent out of the country. The project involves genome data and clinical data from a multitude of clinical and scientific databases across Europe and will focus on cancer, infectious diseases, rare diseases, and other genetically relevant diseases and health issues. The project is financed by the EU and the participating countries.
The Genome of Europe (GoE) project is also a part of the implementation of the 1+MG initiative. The aim of the GoE is to build a network of genomic reference cohorts across the population of Europe. The intention is to include at least 500,000 people from across Europe. The reference cohorts are meant to be representative of the population residing in each of the countries involved.